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Variants in your GLP1R gene, GIPR pathway, and other metabolic markers influence how strongly your body responds to semaglutide

doi: 10.1016/S0140-6736(08)61162-9 [DOI] [PubMed] [Google Scholar] 15

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Clinical data shows that restarting semaglutide after discontinuation produces weight loss similar to initial treatment, though some patients may require slightly higher doses due to reduced sensitivity
