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Since aspirin is often used to prevent heart attacks, cardiologists frequently prescribe it, especially for patients at risk of cardiovascular disease

Slow dose escalation reduces nausea compared to rapid titration

Retatrutide also reduced pain in patients with knee osteoarthritis, with Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain scores dropping by as much as 4.5 points, a 75.8% reduction with the 9 mg dose, compared with a 2.4 point (40.3%) reduction for placebo