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A UCLA study published in ACR Open Rheumatology found that GLP-1 receptor agonists such as semaglutide and tirzepatide may reduce rheumatoid arthritis activity and cardiovascular risk factors in people with obesity, suggesting potential dual benefits for metabolic and inflammatory health.

GLP-1 therapies for weight loss & wellness | Semaglutide & more

Can supplements enhance the long-term efficacy of GLP-1 medications

In a study of more than 1,600 adults with type 2 diabetes, those who received the highest dose of orforglipron on average shed 10.5% of their weight.

Recent 2026 clinical data reveals semaglutide's potential role in reducing hepatic fat accumulation and improving liver enzyme levels in patients with metabolic dysfunction