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As many of these products are peptides, similar half-life extension strategies as were used for GLP-1 products will likely be employed in their design

Month 4-6: Reassess both therapies

Section 503A pharmacies had until April 2025, and Section 503B facilities had until May 2025 to comply

Percentages are rounded up to one decimal place BID two times a day, BMI body mass index, BMOD intensive behavior modification, GLP-1RA glucagon-like peptide 1 receptor agonist, IBT intensive behavioral therapy, NR not reported, OAD oral antihyperglycemic drug, PT phentermine-topiramate, QD once-daily, TID three times per day a Based on patients achieving 5% weight loss during the run-in period b NB16: sustained-release naltrexone 16 mg per day plus sustained-release bupropion 360 mg per day combined in fixed-dose tablets

10.1016/S2213-8587(20)30113-3 [DOI] [PubMed] [Google Scholar] Lachey, J