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1.9.1 Role of the gut neuroendocrine system in appetite regulation Several neural, hormonal and psychological factors control the complex process known as appetite

3,4 In contrast, in Parkinson's disease (PD), neuronal deposits of -synuclein are present and form the primary structural component of Lewy body fibrils that are characteristic of the disorder, whereas in Huntington's disease (HD), cytoplasmic and nuclear deposition of the huntingtin protein and fragments thereof are found

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However, increasingly, data on SGLT2 inhibitors have shown renal and heart failure benefits in people without diabetes, suggesting that people with type 1 diabetes and these comorbidities may also benefit

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