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For years, researchers avoided glucagon activation because glucagon raises blood sugar, which seemed counterproductive for a metabolic medication

However, it must be stressed that, despite the lack of reproductive improvement, even low doses of GLP1/E were sufficient to markedly improve the metabolic perturbations in PWA mice, thus defining an optimal scenario for occasions in which the main therapeutic objective would be metabolic normalization rather than reproductive rescue, as is actually the case for most women with PCOS, without pregnancy desire, which are submitted to continued hormonal contraception plus metformin treatment

Sergey Terushkin, MD, FACS Board-Certified General & Bariatric Surgeon Dr

Drug Interactions: GLP-1 medications can interact with other drugs, particularly those affecting blood sugar

These lawsuits are still underway, but the gravy train has largely already come to a end