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doi: 10.1111/dom.14566 [DOI] [PMC free article] [PubMed] [Google Scholar] 55
Definition, epidemiology and classification of diabetes in children and adolescents
In HEK293 cells expressing human GIP receptor or GLP-1 receptor, tirzepatide potently stimulated cAMP accumulation by both receptors, and the potency of tirzepatide was similar to that of native GIP and approximately 13-fold weaker than that of GLP-1 in these assays [88]
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The comparison between GLP-1RA and SGLT-2 inhibitors also show no difference in their risk for MACE (RR = 0.98, 95% CI 0.911.07)
