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21 Although the long-term retinal effects of GLP-1RA in DR arent fully understood at this time, an ongoing trial is investigating the extended effect of semaglutide on DR after 5 years of treatment

Such lipotoxicity induces cardiotoxic effects through bioactive sphingolipids like ceramides and diacylglycerols (DAGs) (82)

Thats why, wherever you look, youll find plenty of recent news about GLP-1 agonists , a class of drugs that lead to often remarkable weight loss

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doi: 10.1016/J.JDIACOMP.2024.108834 101 VarnumAAPozziEDeebelNAEvansAEidNSadeghi-NejadHet al
