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The most commonly reported adverse events were gastrointestinal-related (GI), and even then, they were generally mild to moderate in severity

The primary search terms included: NAFLD or NASH or MASLD or MASH AND incretin therapies or GLP-1 receptor agonists or GIP receptor agonists or glucagon receptor agonists or dual agonism or triple agonism

Mood improvements may result from better glycaemic control, weight loss, improved physical health, and enhanced self-esteem rather than direct effects on serotonin or other mood-regulating neurotransmitters

Duration and monitoring effects Most clinical trials lasted one year or less