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Description
Why direct conversion is problematic Semaglutide and tirzepatide have different receptor binding profiles, different potencies at the GLP-1 receptor, and tirzepatide has an additional receptor target entirely

317 , E1081E1093 (2019)

And when your appetite is smaller, every bite counts
Additionally, GLP-1RAs reduce the expression of several pro-inflammatory cytokines, including IL-2, IL-17a, IL-6, IFN, and TNF [20,21,24,25]

This scenario was illustrated in our previous dynamic study on GCGR 15
