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Early evidence suggests it is generally well-tolerated, with most side effects being mild to moderate gastrointestinal symptoms (such as nausea, diarrhoea, or constipation)

They can be minimized through gradual dose titration

Out-of-pocket costs are the strongest predictor of abandonment: High OOP costs drive non-adherence, especially in obesity, where coverage is limited and stigma persists

Avoiding these foods is generally advisable, although certain subcategories of ultra-processed foods may have neutral or net positive health effects (e.g., those rich in whole grains, fruit, yogurts, or seafood), depending on their ingredients, processing, and additives [294,295]

But it is a peptide formulation that must be taken on an empty stomach with restricted water intake