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Metabolic associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), and metabolic-associated steatohepatitis (MASH), formerly known as non-alcoholic steatohepatitis (NASH), are conditions linked to obesity and insulin resistance

If chronic fatigue persists, it may indicate an ongoing infection or complications requiring medical attention

At 24 weeks, the mean relative change from baseline in liver fat was a 42.9% reduction in the 1 mg group, a 57.0% reduction at 4 mg, an 81.4% reduction at 8 mg, and an 82.4% reduction at the 12 mg dose

In general, SGLT2 inhibitors are well tolerated and the most common adverse effect is an increased risk of mycotic genital infections by about four- to sixfold versus placebo or active comparator, and this is seen in both women and men [26, 32]