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The only literature-reported phase 1 clinical study to date was recently conducted with PF-06882961
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Bonds JA, Shetti A, Stephen TKL, Bonini MG, Minshall RD, Lazarov O
One patient developed bilateral papillitis, which involves swollen optic nerves that can cause impaired vision, and another had paracentral acute middle maculopathy, which leads to a blind spot in the retina
