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Exenatide stretched that measure to about 2.5 hours3 sufficient for therapy but requiring twice-daily injections that placed a significant burden on patients

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In our practice (SN), we routinely use gastric ultrasound (GUS) to guide clinical decision-making, supported by a dedicated team of credentialed POCUS experts available in the operating room

This interval aligns with recommendations from the Bone Health and Osteoporosis Foundation (BHOF) and allows sufficient time to detect clinically meaningful changes in bone density while enabling timely intervention if significant loss is identified

For researchers currently using retatrutide, the best approach is informed engagement