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Lilly said in an email that while both target metabolic disease, tirzepatide is a GIP/GLP-1 dual agonist injectable, whereas orforglipron is a selective, oral GLP-1 receptor agonist

The risk of suicide or suicide attempts was lower during both the initial exposed period (0-12 months) and late exposed period (13-24 months) compared to the pretreatment period (Fig

None of these are available yet, but they represent where the field is heading over the next two to three years

GIP is an incretin hormone, just like GLP-1, that helps regulate blood sugar levels

Key findings, including the potential protective effects of GLP-1RAs on schizophrenia, anxiety disorders, and autism, were consistently observed across multiple independent datasets, reinforcing the robustness and reproducibility of the results