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The recommended maintenance dose of tirzepatide for weight management is 5 mg, 10 mg, or 15 mg once a week , depending on how your body responds to medication and how well you tolerate it

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What the research shows In the SURMOUNT-1 trial, adults taking once-weekly tirzepatide lost an average of about 15% to 21% of their body weight over 72 weeks depending on dose

Based on current clinical evidence and regulatory data from the Medicines and Healthcare products Regulatory Agency (MHRA) and European Medicines Agency (EMA), there is no evidence of a clinically meaningful effect of Mounjaro (tirzepatide) on cortisol levels

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