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Tried phentermine 37.5 mg daily 9/2025 to 11/2025, discontinued due to intolerable insomnia and palpitations (documented in chart note 11/18/2025)

If tirzepatide directly caused insomnia through receptor activity, you would need to either reduce the dose, change medications, or add a sleep medication

Importantly, pharmacists must only use the medicine as a single-dose vial when administering it to patients, said Ms Fairjones

Methods The SUMMIT primary results, trial protocol and statistical analysis plan have been published, and the protocol and statistical analysis plan are included in Supplementary Information 16