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J., Rosenstock J., et al

Better known by its brand names Ozmepic and Wegovy, its sales growth at one point made Novo Nordisk the most valuable company in Europe

They work by mimicking the action of the hormone GLP-1, which helps regulate blood sugar levels

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These results, using either pharmacology or mouse genetics, show that reduction in CNS GIPR signalling can positively impact peripheral tissue metabolism