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[1] [3] Given that obesity is itself a major cardiovascular risk factor, significant weight loss is generally associated with improvements in blood pressure, lipid profiles, and markers of systemic inflammation, all of which may benefit heart health

Protein is especially important on GLP-1 because it helps protect lean muscle during weight loss
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This range gives researchers flexibility depending on the scale and duration of their retatrutide protocols

A UK decision could come around the end of 2026 or early 2027, though no date is confirmed