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It also reinforces a point I raised previously: that the clinical conversation at the point of prescribing needs to account for the individual patients baseline muscle mass and age-related risk profile, not simply their weight and BMI

Instead of waiting until you feel thirsty, try to build fluids into your day before you are out in the heat, before you exercise, and before symptoms begin

Bavbek S, Ataman , Aknc A, Castells M

A recent report demonstrated that peripubertal-stressed male mice exhibit increased adiposity, which triggers diminished NAMPT protein levels in adipose tissue and decreased levels of circulating eNAMPT, contributing to lifelong reductions in sociability [86]

While anxiety is not an established side effect of Zepbound, patients and clinicians should remain vigilant for other potential mental health changes during treatment