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Vniant, M.M

(8) Excess body weight increases the mechanical load on weight-bearing joints, accelerating cartilage wear and joint degeneration, and contributing to a pro-inflammatory state that further exacerbates joint damage
A-listers, like Sofia Vergara, Adele, and Rebel Wilson, have all been rumored to be using Ozempic for weight loss

doi: 10.1111/dom.15896 78 HuangYNLiaoWLHuangJYLinYJYangSFHuangCCet al

The underlying mechanism of this phenomenon was down-regulation of ACAT1 and CD36 and ABCA1 up-regulation