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Description
Adaptive designs allow for planned modifications in one or more aspects of the study design based on response in earlier phases
Diabetes Metab Syndr 13(4):24632468
445 participants: 12 mg: average 28.7% body weight loss WOMAC knee pain scores dropped by up to 75.8% More than 1 in 8 patients became completely pain-free Systolic blood pressure improved by 14.0 mmHg TRANSCEND-T2D-1 Type 2 diabetes (40 weeks) Published March 2026
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Tong Q, Ye CP, Jones JE, Elmquist JK, Lowell BB
Serious but rare risks include pancreatitis and thyroid effects
