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Bahr said her company health plan wouldn't cover drugs that could help with weight loss

It's a constellation of symptoms that we see from, not only the rapid weight loss, which is what we're learning, but also some specific changes that we're seeing in the skin that are likely a consequence of the medication, Henry said

In the Phase 3 ATTAIN-1 trial published in the New England Journal of Medicine in 2025, once-daily orforglipron produced mean body weight reductions of 7.5% (6 mg), 8.4% (12 mg), and 11.2% (36 mg) at 72 weeks, compared with 2.1% for placebo

Maryland's stakeholder council heard an overview by Brian Link of Three Axis Advisors about drug pricing and the supply chain

This is expected with any GLP-1 receptor agonist because slowing gastric emptying and suppressing appetite inevitably affects digestive function