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Can GLP-1 be Combined with Other Weight Loss Treatments

No international regulatory body has approved retatrutide for any indication
doi:10.1007/s11695-018-3525-0 Alberga AS, Edache IY, Forhan M, Russell-Mayhew S

Acknowledgements This work was supported by grants BFU2017-83934-P, PID2020-118660GB-I00, and PID2021-126915 OA-I00 (Agencia Estatal de Investigacin, Spain

By engaging the GLP-1 receptor (and, for tirzepatide-based compounds, also the GIP receptor), it slows gastric emptying, blunts post-meal glucose spikes, and increases satiety signaling in the hypothalamus
