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Funding The author(s) declare that no financial support was received for the research and/or publication of this article

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The immunopathogenesis is driven by a predominance of T helper (Th)1-mediated immune responses, with elevated interferon- (IFN-) production and impaired function of regulatory T cells (Tregs), which normally restrain autoreactive lymphocytes [11,12]

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symptoms of gallbladder disease (right upper abdominal pain, especially after meals, with nausea)

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