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Panion & BF Biotech Inc.), cultured for 5 days

In CRPC, co-targeting GLP1R and AR could be an efficacious strategy for decreasing ARSI-resistance and improving outcomes for prostate cancer patients who have progressed on ARSI therapies (Figure 4 A, C-D)

The problem is that sub-therapeutic doses do not produce the metabolic changes needed for meaningful weight loss

It is unclear if moderate alcohol consumption causes metabolic syndrome, but metabolic syndrome makes alcohol-related liver conditions more severe

Similar findings emerged from the STEP weight management trials, where heart rate elevations of comparable magnitude were documented