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This guidance reflected the limited evidence available at the time, consisting primarily of case reports and small case series [40]

Clinical experience suggests that some individuals experience increased tiredness, particularly during treatment initiation or dose escalation

For optimal results, we recommend taking Trim Biome GLP-1 consistently for at least 90 days

However, individuals with a personal history of medullary thyroid carcinoma or MEN2 should avoid these medications, and those with a family history should consult with a specialist before proceeding

Novo Nordisk is also investigating a triple agonist of GLP-1, GIP, and glucagon receptors