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The study lasted 40 weeks and compared Tirzepatide to semaglutide, a well-known diabetes drug that works on the GLP-1 system alone

[3] Datamonitor Healthcare Report 2023

PARTICIPANTI Demografia e caratteristiche cliniche dei partecipanti allinizio del trial

SAN DIEGO Adults with obesity and type 2 diabetes achieved a 14.7% weight loss at 72 weeks with 15 mg tirzepatide, according to data from the SURMOUNT-2 trial presented at the American Diabetes Association Scientific Sessions

The mechanism involves inhibition of catechol-O-methyltransferase (COMT), which extends norepinephrine activity and slightly increases metabolic rate