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Early human trials provide signals of target engagement, such as preserved cerebral glucose metabolism, altered inflammatory biomarkers, and slowed brain atrophy, although clinical outcomes to date remain mixed and trials in rarer disorders are sparse

The starting dose is 3mg, which increases to 7mg after 30 days, with a maximum dose of 14mg based on your healthcare providers assessment

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The Gut Microbiota Regulates Hypothalamic Inflammation and Leptin Sensitivity in Western Diet-Fed Mice via a GLP-1R-Dependent Mechanism

In the subgroup of 34 patients whose HS treatments remained unchanged for 12 months prior to M6, all outcomes demonstrated statistically significant improvement