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Behavioral and psychological interventions address the cognitive and emotional aspects of eating behaviors

evaluated serum extracellular vesicles as part of a secondary analysis [90], expanding on the positive primary clinical trial outcomes [87]

Preclinical and clinical studies have demonstrated that GLP-1 receptors expressed in myocardial and vascular endothelium tissue play a fundamental role in the cardioprotective effect of GLP-1 RAs, lowering the risk of major cardiovascular events, heart failure, and kidney complications in adults with and without diabetes [4]

Substantial evidence supports that peptide-mediated GLP-1 secretion is a Ca 2+ sensitive process and involves L-cell signaling via the Ca 2+ sensing receptor (CaSR) and the peptide transporter 1 (PEPT1) [302]

Int J Obes (Lond) (2013) 37(10):13918
