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However, Wegovy is FDA-approved specifically for chronic weight management and physician-supervised programs typically use it with a structured dosing protocol, metabolic monitoring, and lifestyle guidance, while Ozempic is primarily used to treat type 2 diabetes and improve blood sugar control and some physicians may prescribe it off-label for weight loss

Recommendations for future research were also proposed

Data availability To ensure independent interpretation of clinical study results and enable authors to fulfil their role and obligations under the ICMJE criteria, Boehringer Ingelheim grants all external authors access to relevant clinical study data

Nausea occurs because GLP-1 receptor agonists slow gastric emptying, which can cause a feeling of fullness or queasiness, especially after eating

Data from 8 randomized controlled trials (6,361 participants) indicated that this level of weight loss could last as long as 3.5 years, although information on long-term safety remains limited