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Common adverse effects reported in clinical trials include: Nausea (occurring in up to 29% of patients) Diarrhea (reported by up to 23% of patients) Vomiting (affecting up to 10% of patients) Constipation (experienced by up to 17% of patients) Abdominal pain and dyspepsia Decreased appetite (an intended therapeutic effect) These gastrointestinal symptoms typically occur most frequently during dose escalation and tend to diminish over time as patients develop tolerance to the medication

The difference is in their FDA-approved indications Mounjaro for type 2 diabetes, Zepbound for weight management and sleep apnea

If you already struggle with delayed emptying, adding a drug that intensifies this is likely to worsen symptoms

Injecting two days early (five days after your last dose) is generally safe since it exceeds the 72-hour minimum gap

Thigh injections nearly halved the rate of nausea compared to abdominal injections