new oral glp 1 agonist The challenge of developing alternatives to Ozempic, Wegovy and Mounjaro Oral Semaglutide Approved to Reduce

Guidelines for the treatment of hypothyroidism: prepared by the American thyroid association task force on thyroid hormone replacement

A systematic review of meta-analyses that evaluate risk factors for dementia to evaluate the quantity, quality, and global representativeness of evidence

While these agents have demonstrated progressively greater weight-loss efficacy in adults, their safety, tolerability, and long-term effects in adolescent populations remain insufficiently characterized

A few highlights: Accelerated eGFR decline during the year preceding a heart failure event Slower decline afterward but still exacerbated A parallel between eGFR slope and NYHA class, suggesting the kidney may be signaling congestion early These findings call for a shift in practice: instead of relying on static eGFR thresholds, tracking its trajectory over time could help us identify at-risk patients sooner and intervene before hospitalization

The FDA awaited ELIXA results, hence the later U.S