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These provide additional context for designing multi-compound protocols involving GHK-Cu

[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Shetty R, Basheer FT, Poojari PG, Thunga G, Chandran VP, Acharya LD

Tissue specific processing of preproglucagon

Among patients with UC, those treated with GLP1RA had lower rates of corticosteroid use (46.6% vs 85.1%), hospitalization (40.9% vs 65.9%), intestinal resection (6.52% vs 20.8%), and mortality (4.6% vs 22%) compared with controls

302,303,304,305 GLP-1R signaling, through PKA, inhibits this process, possibly by promoting IB stability or inhibiting its phosphorylation, thus reducing NF-B activation and nuclear translocation