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HN treatment decreased cytokine (tumor necrosis factor alpha, interleukin gamma [IFN-])-induced -cell apoptosis measured by caspase 3/7 activity, improved glucose tolerance measured by intraperitoneal glucose tolerance test (IPGTT), lowered the degree of insulitis, and delayed the onset of diabetes in female NOD mice [29]
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More studies are required to understand whether and how exogenous cannabis administration, as well as different components of the endocannabinoid system, may have direct and/or indirect influences on the GLP-1 system
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