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[68] Researchers cautioned against causal interpretation from this study, citing confounding effects, methodological concerns and a 2020 meta-analysis of randomized controlled trials which showed no increased risk

Firkins SA, Chittajallu V, Flora B, Yoo H, Simons-Linares R

In addition, lower estrogen levels are associated with lower dopamine and serotonin, which can affect motivation and workout satisfaction

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The mechanism of action of Saxenda involves several physiological pathways: Appetite suppression : Liraglutide acts on GLP-1 receptors in the hypothalamus and other brain regions involved in appetite control, leading to increased satiety and reduced hunger