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Weight loss (by any means) causes a release of stored fat from fat cells, but the fat cells remain there as storage vessels, waiting for a calorie excess to fill back up again

Blood sugar spikes When you have T2D, any sugary beverage can cause your blood glucose to spike

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In rare cases, a healthcare provider may adjust timing based on: Strong tolerance at low dose Medical history Blood sugar response (for diabetes management) Individual treatment goals But this is always clinician-guided , not self-adjusted

By understanding how Effexor might affect semaglutide, you can take an active role in your treatment