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In the crypts, multiple signaling pathways in the niche, including Wnt, BMP, Notch, EGF, and Eph/Ephrin play important roles in the regulation of self-renewal and differentiation of intestinal stem cells (ISCs) [19]
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[DOI] [PubMed] [Google Scholar] 143.Wadden TA, Chao AM, Machineni S, Kushner R, Ard J, et al
