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Oxyntomodulin has been shown to reduce bodyweight and food intake in rodents and humans [11, 12] and to increase energy expenditure in people with obesity [13], via activity at both receptors

Diverticulosis is common but rarely causes symptoms or problems during a patients lifetime

Resistance training 3x/week plus 150 minutes/week of moderate cardiovascular activity (you can talk but cant sing)

Ongoing communication and timely dietary adjustments can reduce side effects by tailoring strategies to patients' individual needs

Patients using oral contraceptives should switch to a non-oral method or add a barrier method of contraception for at least 4 weeks after initiating tirzepatide and after each dose escalation