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Myostatin/activin pathway antagonism: molecular basis and therapeutic potential

Similarly, at week 12, reduction in HbA1c from baseline was significantly greater with DAPA + SITA + MET ER compared to SITA + MET SR ( p = 0.0006) and DAPA + MET ER ( p = 0.0276)

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Notably, 41% of patients who had not been on any antidiabetic treatment required their first antidiabetic medication following treatment with pasireotide (64, 65)

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