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If the patient can tolerate it, the dose is escalated to 1.7 mg (Wegovy) or 2 mg weekly (Ozempic) for the next four weeks and up to a maximum of 2.4 mg once weekly (Wegovy) afterwards as a maintenance dose

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Step three: combination and intensification For patients who do not reach their targets on either medication alone, combining basal insulin with a GLP-1 agonist is an increasingly popular strategy

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Striatal dopamine in anhedonia: a simultaneous [11C]raclopride positron emission tomography and functional magnetic resonance imaging investigation

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