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For patients with an A1C of 6.5% to 7.5%, metformin is the preferred initial agent, with GLP-1 receptor agonists, dipeptidyl-peptidase-4 (DPP-4) inhibitors, thiazolidinediones (TZDs), or an alpha-glucosidase inhibitor listed as viable alternatives

2023, doi: 10.1111/dom.15167

Therefore, the practice of microdosing GLP-1 medications is experimental and off-label and is not approved by the FDA

Moreover, Elkind-Hirsch et al
