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Now the challenge was to find a small molecule that also fits that pocket

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In addition to todays resource, please see and review the New York Times article, The Risks of Taking Drugs Like Ozempic When Youre Over 65: Medications that cause drastic weight loss raise specific concerns for older adults

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Akkermansia muciniphila produces P9, a small protein that interacts with intercellular adhesion molecule 2 to increase thermogenesis and glucagon-like peptide-1 secretion in mice.

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