dpp4 and glp 1 mechanism of action PDB-101: Diabetes Mellitus: Diabetes Mellitus: undefined: Mechanisms underlying GLP-1, GIP, and

[DOI] [PMC free article] [PubMed] [Google Scholar] 8.Kim Y.H., Kim S.M., Han K.D., Jung J.H., Lee S.S., Oh S.W., Park H.S., Rhee E.J., Lee W.Y., Yoo S.J

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Subtle dynamics allows the C-terminal of the ligand to access the ECD binding site, and the binding of the ligand triggers further dissociation between the ECD and TMD, allowing the N-terminal to enter the orthosteric pocket in the TMD and activate the receptor

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