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Weight regain reality Research shows that most people regain a significant portion of lost weight within a year of stopping GLP-1 medications

Studies in bariatric surgery patients (who experience similar rapid weight loss) show that 25-30% develop new gallstones within one year, though only a fraction experience symptoms like pain or inflammation

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Yeh H, Lin C, Li YR, Yen CL, Lee CC, Chen JS, Chen KH, Tian YC, Liu PH, Hsiao CC

Davies MJ, Aroda VR, Collins BS, Gabbay RA, Green J, Maruthur NM, Rosas SE, Del Prato S, Mathieu C, Mingrone G