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Description
Other contemporary studies, such as the EXSCEL and FREEDOM trials evaluated the cardiovascular effects of exenatide, a GLP-1 RA (80, 81)
Wegovy producing 14.9% average weight loss in its Phase 3 trial was, at the time, the most effective obesity medication ever approved
instead, they provide nutritional ingredients traditionally used to support metabolic wellness and healthy lifestyle habits
However, there was no significant difference in adverse CVEs or all-cause mortality when compared with those taking SGLT2 inhibitors
The preclinical animal model data suggested that the glucose-lowering, lipid-lowering and insulin secreting effects were greater than those in GLP-1 receptor agonists [50]
