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GLP-1 receptor activation has been associated with improved endothelial function in some studies

[DOI] [PubMed] [Google Scholar] 40.Nielsen F., Mikkelsen B.B., Nielsen J.B., Andersen H.R., Grandjean P

These studies demonstrated that approximately 2530% of total weight loss comprised lean mass , which falls within the expected range for substantial weight loss interventions

they will be most beneficial to patients who also maintain a healthful diet and commit to regular exercise
