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Claims may be stronger when the injury resulted in long-term impairment, surgical procedures, significant financial losses, or permanent health limitations

It is important to note that the upregulation of IL-33 observed in some GLP-1 studies does not universally guarantee mucosal defense, as IL-33 can also drive potent Th2 inflammatory responses depending on the tissue context ( In 2024, Sun and colleagues investigated GLP-1 receptor agonists in a DSS-colitis model