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142 This has important implications for individuals with IBD, as delayed gastric transit may impair the absorption of orally administered therapies such as 5-ASA and thiopurines

Theoretically, the combination of retatrutide with a ketogenic diet could produce even more robust ketosis than either intervention alone, though clinical data on this specific combination is not yet available

Most protocols start with the lowest available dose and increase gradually over weeks to months

Statistical analysis We used propensity score matching to create balanced comparison groups and estimate causal effects while controlling for measured confounders (see previous section)

While compounded medications are not FDA-approved like brand names, 503A compounded GLP-1s have demonstrated equivalent efficacy and safety profiles in clinical use