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Besides the complex pharmacological interplay between the GIP receptor targeting ligands and the receptor addressed above, another aspect of GIP biology is the tissue-specific actions, which might affect the clinical results of GIP targeting treatments

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Within the SGLT2i + CKD group, eGFR improved from 45.5 ml/min per 1.73 m 2 at baseline to 47.0 ml/min per 1.73 m 2 at 5 years

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